α-C-H photoalkylation of a glucose derivative in continuous flow

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Complementary chemoenzymatic routes to both enantiomers of febrifugine

Publication
Org. Biomol. Chem. (2009), 7(14), 2976-2980
Year
2009
Customer
Chiralix
Symeres authors
Richard Blaauw
Publication

Complete Deracemization by Attrition-Enhanced Ostwald Ripening Elucidated

Publication
Angew. Chem. Int. Ed., 2008, 47, 6445-6447
Year
2008
Customer
DSM
Symeres authors
Michel Leeman, Richard Kellogg
Publication

The Thulium Complex of 1,4,7,10-Tetrakis{[N-(1H-imidazol-2-yl)carbamoyl]methyl}-1,4,7,10-tetraazacyclododecane (dotami) as a ParaCEST Contrast Agent

Publication
Chemistry & Biodiversity 2008, 5, 8, 1505-1512
Year
2008
Customer
TU Eindhoven
Symeres authors
Wolter ten Hoeve
Publication

Structural Aspects of Nucleation Inhibitors for Diastereomeric Resolutions and the Relationship to Dutch Resolution

Publication
Angew. Chem. Int. Ed., 2008, 1287-1290
Year
2008
Customer
DSM
Symeres authors
Michel Leeman, Elly Smits, Jim van Wiltenburg
Publication

Large-Scale Synthesis of the Glucosylceramide Synthase Inhibitor N-[5-(Adamantan-1-yl-methoxy)-pentyl]-1-deoxynojirimycin

Publication
Org. Process Res. Dev. 2008, 12, 414
Year
2008
Customer
Symeres authors
Publication

Explanation for the Emergence of a Single Chiral Solid State During Attrition-Enhanced Ostwald Ripening: Survival of the Fittest

Publication
Cryst. Growth Des., 2008, 8, 1675-1681
Year
2008
Customer
Radboud University Nijmegen
Symeres authors
Richard Kellogg
Publication

Emergence of a Single Solid Chiral State from a Nearly Racemic Amino Acid Derivative

Publication
J. Am. Chem. Soc., 2008, 130, 1158-1159
Year
2008
Customer
DSM
Symeres authors
Michel Leeman, Richard Kellogg
Publication

Attrition-Enhanced Deracemization of an Amino Acid Derivative That Forms an Epitaxial Racemic Conglomerate

Publication
Angew. Chem. Int. Ed., 2008, 47, 7226
Year
2008
Customer
DSM
Symeres authors
Richard Kellogg
Publication

Synthesis of a Naturally Occurring Diene-Containing Amino Acid and Its Glutamyl Dipeptide via N-Acyliminium Ion Chemistry

Publication
Eur. J. Org. Chem., 2008(5), 914-924
Year
2008
Customer
Chiralix
Symeres authors
Richard Blaauw
Publication

N,N-Acetals as N-Acyliminium Ion Precursors: Synthesis and Absolute Stereochemistry of Epiquinamide

Publication
Org. Lett. (2008), 10(18), 4001-4003
Year
2008
Customer
Chiralix
Symeres authors
Richard Blaauw
 
 

Development Centres of Excellence Network Lead Optimization Hit Generation Lead Optimization
 
 
 
 
 

Development Centres of Excellence Network Lead Optimization Hit Generation Lead Optimization
 
 
 
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