α-C-H photoalkylation of a glucose derivative in continuous flow

Publication

Discovery of Small Molecule Vanin Inhibitors: New Tools To Study Metabolism and Disease

Publication
ACS Chem. Biol. (2013), 8(3), 530-534
Year
2013
Customer
Chiralix
Symeres authors
Richard Blaauw
Publication

Combination of Pantothenamides with Vanin Inhibitors as a Novel Antibiotic Strategy against Gram-Positive Bacteria

Publication
Antimicrob. Agents Chemother. (2013), 57(10), 4794-4800
Year
2013
Customer
Chiralix
Symeres authors
Richard Blaauw
Publication

Correlation between activation of PPARγ and resistin downregulation in a mouse adipocyte cell line by a series of thiazolidinediones

Publication
Toxicology in Vitro (2013), 27(5), 1425-1432
Year
2013
Customer
Chiralix
Symeres authors
Richard Blaauw
Publication

Pharmacological Validation of Trypanosoma brucei Phosphodiesterases as Novel Drug Targets

Publication
J. Infect. Dis. 2012, 206(2), 229-237
Year
2012
Customer
Institute of Infection, Immunity and Inflammation, College of Medical,
Symeres authors
Geert Jan Sterk
Publication

Pasteur’s tweezers revisited: On the mechanism of attrition-enhanced deracemization and resolution of chiral conglomerate solids

Publication
J. Am. Chem. Soc., 2012, 134, 12629-12636
Year
2012
Customer
University of California
Symeres authors
Richard Kellogg
Publication

A Chiral Self-Assembled Monolayer Derived from a Resolving Agent and its Performance as a Crystallization Template for an Organic Compound from Organic Solvents

Publication
Chem. Eur. J. 2012, 1521-3765
Year
2012
Customer
Symeres authors
Maarten van der Meijden, Richard Kellogg
Publication

Heat Shock Protein–Inducing Compounds as Therapeutics to Restore Proteostasis in Atrial Fibrillation

Publication
Trends in Cardiovascular Medicine 2012, 22(3), 62-68
Year
2012
Customer
Symeres authors
André Heeres, Lizette Loen, Jean-Paul Seerden
Publication

Crystallization Techniques to Obtain Pure Enantiomers: From Resolution to Grinding

Publication
Comprehensive Chirality 1st edition, 2012, 9.16, 367-399
Year
2012
Customer
Symeres authors
Richard Kellogg, Michel Leeman
Publication

Complete Deracemization of Proteinogenic Glutamic Acid Using Viedma Ripening on a Metastable Conglomerate

Publication
Cryst. Growth Des. (2012), 12(11), 5796-5799
Year
2012
Customer
Chiralix
Symeres authors
Richard Blaauw
Publication

Novel Procedure for the Coupling of Sterically-hindered Electron-deficient Anilines to the 6-Position of the Purine Core

Publication
Synth. Comm. 2011, 41, 3246-3250
Year
2011
Customer
Janssen Pharma-ceutica N.V. (CMD)
Symeres authors
Ruben leenders, Dirk Vandenput
 
 

Development Centres of Excellence Network Lead Optimization Hit Generation Lead Optimization
 
 
 
 
 

Development Centres of Excellence Network Lead Optimization Hit Generation Lead Optimization
 
 
 
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