Large-Scale Cyclopropanation of Butyl Acrylate with Difluorocarbene and Classical Resolution of a Key Fluorinated Building Block

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A Ninhydrin-Type Urea Sorbent for the Development of aWearable Artificial Kidney

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Macromol. Biosci. 2020, 1900396
Year
2020
Customer
Utrecht University
Symeres authors
Dennis Verdijk
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Examining sterically demanding lysine analogs for histone lysine methyltransferase catalysis

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Scientific Reports volume 10, Article number: 3671 (2020)
Year
2020
Customer
Radboud University
Symeres authors
Anita Wegert
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The Evolving Outsourcing Landscape in Pharma R&D – Different Collaborative Models and Factors to Consider when Choosing a Contract Research Organization

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J. Med. Chem., 2020, xxx
Year
2020
Customer
MercachemSyncom
Symeres authors
Bart DeCorte
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Pre-clinical lead optimization of a 1,2,4-triazole based tankyrase inhibitor

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J. Med. Chem., 2020, xxxx
Year
2020
Customer
Oslo University
Symeres authors
Ruben Leenders, Piotr Nieczypor, Sjoerd Aertsen, Eddy Damen, Anita Wegert
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Open Innovation and Pharma R&D Transformation: New Opportunities for Academic Research Institutions, Contract Research Organizations, and Biotech Companies

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MEDCHEM NEWS Vol.30 No.1
Year
2020
Customer
MercachemSyncom
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Luc van Hijfte, Norimasa Morita, Bart DeCorte, Marleen Dolman
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Preclinical Lead Optimization of a 1,2,4-Triazole Based Tankyrase Inhibitor

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J. Med. Chem. 2020, 63, 6834-6846
Year
2020
Customer
Oslo University
Symeres authors
Ruben Leenders, Piotr Nieczypor, Sjoerd Aertsen, Eddy Damen, Anita Wegert
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The synthesis of 13C6-labeled l-thyronine, 3,5-diiodothyronine, 3,3′,5-triiodothyroacetic acid and 3,3′,5,5′-tetraiodothyroacetic acid

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Tetrahedron 2020 (76), 33, 131352
Year
2020
Customer
Erasmus MC
Symeres authors
Gregor Pilzak, Toine van den Bergh, Tommi Meulemans
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Performance Analysis and Model-Free Design of Deracemization via Temperature Cycles

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Org. Process Res. Dev. 2020
Year
2020
Customer
ETH institute
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Michel Leeman, Richard Kellogg
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Enantiospecific Solid Solution Formation Triggers the Propagation of Homochirality

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Angew. Chem. Int. Ed. 2020, 59, 1 – 6
Year
2020
Customer
AMOLF
Symeres authors
Michel Leeman, Richard Kellogg
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Scalable Synthesis of 17S-FD-895 Expands the Structural Understanding of Splice Modulatory Activity

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Cell Reports Physical Science 2020 (1), 12, 100277
Year
2020
Customer
UCSD
Symeres authors
Mark Verhaar, Martijn Slagt, Dominika Bachera, Minze Rispens, Remco Hofman, Vincent de Boer, Rory van der Hulst Rutger Bus, Pieter Hiemstra
 
 

Development Centres of Excellence Network Lead Optimization Hit Generation Lead Optimization
 
 
 
 
 

Development Centres of Excellence Network Lead Optimization Hit Generation Lead Optimization
 
 
 
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