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Enantiomers of 6-[(4-chloro-phenyl)-hydroxy-(3-methyl-3H-imidazol-4-yl)-methyl]-4-[3-(3-hydroxy-3-methyl-but-1-ynyl)-phenyl]-1-methyl-1H-quinolin-2-one and salts thereof, useful in the treatment of cancer

Number
US7176315 B2
Year
2002
Customer
Pfizer Inc.
Site
Groningen
Department
Discovery
MCS People
Kees Pouwer
Patent

Novel processes for the preparation or (R)-alpha-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol

Number
US20020151717
Year
2002
Customer
Aventis Pharmaceuticals Inc.
Site
Groningen
Department
Development
MCS People
Jan Koek
Patent

Method for the preparation of enantiomerically enriched compounds

Number
WO 0142173
Year
2000
Customer
DSM
Site
Groningen
Department
Discovery
MCS People
Jean-Paul Seerden, Marcel van der Sluis
Patent

1-Fenyl-3-oxopropaan-1-sulfonzuren en –sulfonaten en zuivere enantiomeren daarvan

Number
NL1012865 / NO42870
Year
1999
Customer
DSM
Site
Groningen
Department
Discovery
MCS People
Hans Wijnberg, Kees Pouwer, José Nieuwenhuijzen, Ton Vries
Patent

Method for making hydroxy-25-ene vitamin D compounds

Number
WO9961417 1999
Year
1999
Customer
Bone Care International, Inc
Site
Groningen
Department
Development
MCS People
Hans Wijnberg, Ton Vries, Kees Pouwer
Patent

Polymer electroluminescent device

Number
WO9921936 1999, EP975710 2000
Year
1999
Customer
Philips
Site
Groningen
Department
Discovery
MCS People
Hans Wijnberg, Wolter ten Hoeve, Karin Spoelstra
Patent

Processes for the preparation of (R)-.agr.-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol

Number
WO9946245 1999
Year
1999
Customer
Hoechst Marion Roussel Deutschland GMBH.
Site
Groningen
Department
Development
MCS People
Jan Koek
Patent

Method of preparing a thiophene-containing or furan-containing conjugated compound and precursor compound used therein

Number
EP867437 1998, US05919951 1999
Year
1998
Customer
Philips
Site
Groningen
Department
Development
MCS People
Wolter ten Hoeve, Hans Wijnberg
Patent

Process for the production of semi synthetic statins via novel intermediates

Number
WO9832751 1998, EP971913 2000
Year
1998
Customer
Gist-Brocades b.v.
Site
Groningen
Department
Development
MCS People
Ton Vries, Hans Wijnberg, Wijnand Faber
Patent

Process for the separation of a mixture of enantiomers

Number
EP838448 1998
Year
1998
Customer
DSM
Site
Groningen
Department
Development
MCS People
Ton Vries, Hans Wijnberg, Erik van Echten

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