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Publication

Counteracting Enantiospecific Behavior of Tailor-Made Additives During Chiral Symmetry Breaking: Growth Inhibition versus Solid-Solution Formation

Publication
Isr. J. Chem. 2021, 61, 1 – 6
Year
2021
Customer
Ardena
Site
Nijmegen
Department
Discovery
MCS people
Michel Leeman, Richard Kellogg
Publication

Discovery of 2,4-1H-Imidazole Carboxamides as Potent and Selective TAK1 Inhibitors

Publication
ACS Medicinal Chemsitry Letters, coming soon
Year
2021
Customer
X-Chem, Inc.
Site
Nijmegen
Department
Discovery
MCS people
Johan Veerman, Yorik Bruseker, Eddy Damen, Erik Heijne, Wendy van Brugge, Koen Hekking, Rob Winkel, Peter van Rijnsbergen
Publication

Scalable Synthesis of 17S-FD-895 Expands the Structural Understanding of Splice Modulatory Activity

Publication
Cell Reports Physical Science 2020 (1), 12, 100277
Year
2020
Customer
UCSD
Site
Groningen
Department
Development
MCS people
Mark Verhaar, Martijn Slagt, Dominika Bachera, Minze Rispens, Remco Hofman, Vincent de Boer, Rory van der Hulst Rutger Bus, Pieter Hiemstra
Publication

A novel pyrimidine forming cyclization

Publication
Tetrahedron Letters 61 (2020) 151369
Year
2020
Customer
Janssen research
Site
Nijmegen
Department
Discovery
MCS people
Ruben Leenders, Marc van de Sande
Publication

A Ninhydrin-Type Urea Sorbent for the Development of aWearable Artificial Kidney

Publication
Macromol. Biosci. 2020, 1900396
Year
2020
Customer
Utrecht University
Site
Nijmegen
Department
Development
MCS people
Dennis Verdijk
Publication

Examining sterically demanding lysine analogs for histone lysine methyltransferase catalysis

Publication
Scientific Reports volume 10, Article number: 3671 (2020)
Year
2020
Customer
Radboud University
Site
Nijmegen
Department
Discovery
MCS people
Anita Wegert
Publication

The Evolving Outsourcing Landscape in Pharma R&D – Different Collaborative Models and Factors to Consider when Choosing a Contract Research Organization

Publication
J. Med. Chem., 2020, xxx
Year
2020
Customer
MercachemSyncom
Site
Department
MCS people
Bart DeCorte
Publication

Pre-clinical lead optimization of a 1,2,4-triazole based tankyrase inhibitor

Publication
J. Med. Chem., 2020, xxxx
Year
2020
Customer
Oslo University
Site
Nijmegen
Department
Discovery
MCS people
Ruben Leenders, Piotr Nieczypor, Sjoerd Aertsen, Eddy Damen, Anita Wegert
Publication

Open Innovation and Pharma R&D Transformation:
New Opportunities for Academic Research Institutions,
Contract Research Organizations, and Biotech Companies

Publication
MEDCHEM NEWS Vol.30 No.1
Year
2020
Customer
MercachemSyncom
Site
Department
MCS people
Luc van Hijfte, Norimasa Morita, Bart DeCorte, Marleen Dolman
Publication

Preclinical Lead Optimization of a 1,2,4-Triazole Based Tankyrase Inhibitor

Publication
J. Med. Chem. 2020, 63, 6834-6846
Year
2020
Customer
Oslo University
Site
Nijmegen
Department
Discovery
MCS people
Ruben Leenders, Piotr Nieczypor, Sjoerd Aertsen, Eddy Damen, Anita Wegert

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Development Centres of Excellence Network Lead Optimization Hit Generation Lead Optimization
 
 
 
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