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Publication

Counteracting Enantiospecific Behavior of Tailor-Made Additives During Chiral Symmetry Breaking: Growth Inhibition versus Solid-Solution Formation

Publication
Isr. J. Chem. 2021, 61, 1 – 6
Year
2021
Customer
Ardena
Site
Nijmegen
Department
Discovery
MCS people
Michel Leeman, Richard Kellogg
Publication

A new approach to produce [18F]MC225 via one-step synthesis, a PET radiotracer for measuring P-gp function

Publication
Khaled Attia, John Carlo Sembrano, Olivier Jacquet, Ton Visser
Year
2021
Customer
UMCG
Site
Groningen
Department
Discovery
MCS people
Garcia-Varela et al. EJNMMI Radiopharmacy and Chemistry (2021) 6:24
Publication

GMP Compliant Synthesis of [18F]Canagliflozin, a Novel PET Tracer for the Sodium−Glucose Cotransporter 2

Publication
J. Med. Chem. XXXX, XXX, XXX−XXX
Year
2021
Customer
UMCG
Site
Groningen
Department
Development
MCS people
Olivier Jacquet, Ton Visser, Andre Heeres, Khaled Attia
Publication

Resolution of a Metastable Racemic Compound of Anhydrous Phencyphos by Hydrate Formation

Publication
Crystals 2021 (11), 1225
Year
2021
Customer
Symeres
Site
Groningen
Department
Discovery
MCS people
Michel Leeman and Richard M. Kellogg
Publication

Discovery of 2,4-1H-Imidazole Carboxamides as Potent and Selective TAK1 Inhibitors

Publication
ACS Medicinal Chemsitry Letters, coming soon
Year
2021
Customer
X-Chem, Inc.
Site
Nijmegen
Department
Discovery
MCS people
Johan Veerman, Yorik Bruseker, Eddy Damen, Erik Heijne, Wendy van Brugge, Koen Hekking, Rob Winkel, Peter van Rijnsbergen
Publication

Exploration of a Nitromethane-Carbonylation Strategy during Route Design of an Atropisomeric KRASG12C Inhibitor

Publication
J. Org. Chem. 2021
Year
2021
Customer
AstraZeneca
Site
Groningen
Department
Development
MCS people
Cati Ferrer
Publication

Modular Medical Imaging Agents Based on Azide–Alkyne Huisgen Cycloadditions: Synthesis and Pre-Clinical Evaluation of 18F-Labeled PSMA-Tracers for Prostate Cancer Imaging

Publication
Chemistry A European Journal 27, 23, 6993
Year
2020
Customer
Dutch Provinces Overijssel and Gelderland
Site
Groningen
Department
Discovery
MCS people
Marten Klopstra, Ton Visser, Keimpe-Oeds van den Berg
Publication

Scalable Synthesis of 17S-FD-895 Expands the Structural Understanding of Splice Modulatory Activity

Publication
Cell Reports Physical Science 2020 (1), 12, 100277
Year
2020
Customer
UCSD
Site
Groningen
Department
Development
MCS people
Mark Verhaar, Martijn Slagt, Dominika Bachera, Minze Rispens, Remco Hofman, Vincent de Boer, Rory van der Hulst Rutger Bus, Pieter Hiemstra
Publication

A novel pyrimidine forming cyclization

Publication
Tetrahedron Letters 61 (2020) 151369
Year
2020
Customer
Janssen research
Site
Nijmegen
Department
Discovery
MCS people
Ruben Leenders, Marc van de Sande
Publication

A Ninhydrin-Type Urea Sorbent for the Development of aWearable Artificial Kidney

Publication
Macromol. Biosci. 2020, 1900396
Year
2020
Customer
Utrecht University
Site
Nijmegen
Department
Development
MCS people
Dennis Verdijk

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