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Publication

Complete Deracemization of Proteinogenic Glutamic Acid Using Viedma Ripening on a Metastable Conglomerate

Publication
Cryst. Growth Des. (2012), 12(11), 5796-5799
Year
2012
Customer
Chiralix
Symeres authors
Richard Blaauw
Publication

Novel Procedure for the Coupling of Sterically-hindered Electron-deficient Anilines to the 6-Position of the Purine Core

Publication
Synth. Comm. 2011, 41, 3246-3250
Year
2011
Customer
Janssen Pharma-ceutica N.V. (CMD)
Symeres authors
Ruben leenders, Dirk Vandenput
Publication

Phosphodiesterase Inhibitors as a New Generation of Antiprotozoan Drugs: Exploiting the Benefit of Enzymes that are Highly Conserved Between Host and Parasite

Publication
Future Med. Chem. 2011, 3, 1289-1306
Year
2011
Customer
Mercachem
Symeres authors
Geert Jan Sterk
Publication

Resolution of Praziquantel

Publication
PLoS Negl Trop Dis 2011, 5(9), e1260
Year
2011
Customer
UNICEF
Symeres authors
Jean-Paul Seerden, Jesse de Gooijer, Kees Pouwer
Publication

A Novel Route to 2,4-Dianilino-substituted Pyrimidines

Publication
Tetrahedron Lett. 2010, 51, 543-544
Year
2010
Customer
Janssen Pharma-ceutica N.V. (CMD)
Symeres authors
Ruben Leenders
Publication

3-(Arylamino)-1,2,4-triazine-5-one: A Novel Synthesis and its Use

Publication
Eur. J. Org. Chem. 2010, 15, 2852-2854
Year
2010
Customer
Janssen Pharma-ceutica N.V. (CMD)
Symeres authors
Ruben leenders, Dirk Vandenput, Remco Zijlmans
Publication

6-Phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile as cathepsin S inhibitors

Publication
Bioorg. Med. Chem. Lett. 2010, 20, 4350–4354
Year
2010
Customer
MSD Newhouse
Symeres authors
Leon van Berkom, Martijn Bastiani, Tommi Meulemans
Publication

Biotransformation-mediated synthesis of (1S)-1-(2,6-dichloro-3-fluorophenyl)ethanol in enantiomerically pure form

Publication
Tetrahedron: Asymmetry 2010, 21, 19, 2408-2412
Year
2010
Customer
Pfizer
Symeres authors
Erik Keller, Renzo Meijer, Gerard Metselaar, Gerlof Kruidhof
Publication

Practical Aspects of Carbon Carbon Cross-Coupling Reactions Using Heteroarenes

Publication
Organic Process Research & Development 2010, 14, 30–47
Year
2010
Customer
DSM
Symeres authors
Vincent Slagt, Richard Kellogg
Publication

The Driving Mechanism Behind Attrition-Enhanced Deracemization

Publication
Angew. Chem. Int. Ed., 2010, 49, 8435-8438
Year
2010
Customer
DSM
Symeres authors
Richard Kellogg
 
 

Development Centres of Excellence Network Lead Optimization Hit Generation Lead Optimization
 
 
 
 
 

Development Centres of Excellence Network Lead Optimization Hit Generation Lead Optimization
 
 
 
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