Webinars

Advancing Discovery Through Scientific Exchange

At Symeres, we believe that innovation in drug discovery is accelerated through collaboration and knowledge sharing. Our webinar series brings together scientists, partners, and thought leaders to explore cutting-edge advances in medicinal chemistry, synthesis, screening and scale-up strategies, development and more.

Each session is grounded in real-world R&D experience and designed for professionals working across the drug discovery and development spectrum—from medicinal chemists and CMC experts to project leaders and biotech innovators.


Past Webinars

Accelerating Medicinal Chemistry by Rapid Analoging

Medicinal chemistry is the art of rapidly evolving initial hits to clinical candidates via smart, information driven multiparametric optimization. The success of such a process largely depends both on the quality of the starting points and on the ability to rapidly generate deep SAR and SPR understanding of the compound series.

The seminar will highlight:

  • how parallel chemistry supports medicinal chemistry endeavors, both it in the area of library design & production and fast analoging initiatives to accelerate the hit exploration and SAR building efforts
  • discuss the advantage of smart library generation, rapid hit expansion and fast analoging
  • when projects may benefit of this particular expertise.

Natural-Product Derived Novel Chemical Space

This webinar features Dr. Bart DeCorte. In this presentation, Dr. DeCorte explores the potential of utilizing natural products as a foundation for drug discovery. He delves into strategies for harnessing the structural diversity of natural compounds to access novel chemical spaces, which can lead to the development of innovative therapeutics.

The session covers and is valuable for:

  • methodologies for modifying natural products to enhance their drug-like properties
  • discusses the integration of these compounds into modern medicinal chemistry workflows.
  • particularly valuable for professionals in pharmaceutical research and development seeking to expand their compound libraries with structurally unique and biologically active molecules derived from natural sources.


In Vivo Pharmacokinetic Experiments in Preclinical Drug Development

Despite a good part of ADME research in drug discovery and preclinical development can be performed using various in silico or in vitro systems, eventually it becomes necessary to evaluate the pharmacokinetic (PK) profile in animals to elucidate in vivo DMPK properties of the drug candidates.

This webinar by Janne Mannilla of Admecope will elucidate:

  • Important considerations when planning PK studies
  • The components of an in vivo PK experiment
  • The most important PK parameters at this stage

Route scouting for kilogram-scale manufacturing of APIs

The webinar by Dr. Martin Strack provides an in-depth exploration of the strategies and considerations involved in developing scalable synthetic routes for Active Pharmaceutical Ingredients (APIs).

Some key takeaways are:

  • Focus on scaling API synthesis from lab to kilogram scale
  • Emphasizes route selection for safety, yield, cost, and efficiency
  • Covers process optimization for reproducibility and robustness
  • Highlights purification, crystallization, and environmental factors
  • Includes real-world case studies from pharmaceutical development


Solid-State Chemistry Part I: Introduction



This webinar, presented by solid-state expert Edwin Aret, offers an insightful introduction to the field of solid-state chemistry. Aimed at professionals in pharmaceutical development, the session delves into the significance of solid-state forms in drug substances, including polymorphs, salts, and co-crystals.

Aret discusses:

  • Techniques for solid-form screening and crystallization,
  • How these processes influence drug stability, solubility, and manufacturability.
  • The integration of solid-state strategies into early-phase drug development to optimize formulation and regulatory outcomes.

Solid-State Chemistry Part II: Optimal form selection by controlled crystallization 

The webinar by Dr. Edwin Aret of MercachemSyncom focuses on advanced strategies for selecting and controlling solid forms of pharmaceutical compounds through crystallization techniques. Dr. Aret emphasizes the critical role of solid-state chemistry in drug development, particularly in optimizing properties like solubility, stability, and manufacturability.

Key topics covered include:

  • Understanding how different crystalline forms (polymorphs) of a compound can influence drug efficacy and stability.
  • Exploring methods to direct the crystallization process to obtain the desired solid form, including temperature control, solvent selection, and seeding strategies.
  • Utilizing techniques such as X-ray diffraction and thermal analysis to characterize solid forms and ensure consistency in production.


Medical imaging and (radio)chemistry

Dive into the fascinating world of Positron Emission Tomography (PET)—a cutting-edge medical imaging technique that visualizes disease processes with remarkable precision. This webinar unpacks the core principles of PET and showcases how radioactive labeled pharmaceuticals play a vital role in capturing detailed images of pathophysiological changes.

This webinar covers:

  • Understand the fundamental physics and technology behind PET imaging
  • Learn how PET visualizes biological processes at the molecular level
  • Explore the critical use of radioactive labeled drugs in enhancing image specificity
  • See real-world examples demonstrating PET’s impact in medical diagnosis and research

Electrosynthesis: Shono oxidation in the synthesis of complex molecules

The webinar by Wouter Nieuwstraten explores the application of Shono oxidation in organic synthesis. This webinar dives into how this elegant electrochemical method transforms protected amines into reactive intermediates, enabling the efficient construction of complex molecules under mild conditions. Perfect for chemists eager to explore sustainable, selective, and cutting-edge tools in organic synthesis, this session highlights real-world applications in natural product and pharmaceutical synthesis. Ready to level up your synthetic toolbox?

Topics covered:

  • Master how Shono oxidation enables efficient, selective functionalization under mild, sustainable conditions.
  • Unlock new pathways for synthesizing complex pharmaceuticals and natural products using electrosynthesis.
  • Gain practical expert insights for applying and scaling cutting-edge electrochemical methods in your lab.

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