Senior Consultant Clinical Pharmacology and Pharmacokinetics

DGr Pharma, member of the Symeres group, is a young and dynamic consultancy company with a very strong client base. DGr Pharma specializes in guiding drug development programs from end lead selection to Phase II clinical development. We are now recruiting for a Senior Consultant of Clinical Pharmacology and Pharmacokinetics for our office in Breda.

Do you want to play a pivotal role in providing strategic clinical pharmacology guidance on our drug development? This position includes modeling to support FIH dose, and development and execution of plans to analyze PK, ADA, drug interaction studies, pharmacodynamics, and population PK.

You will bring strong writing skills to craft clear, precise documents—from non-clinical and clinical protocols to statistical analysis plans, clinical study reports, abstracts, and presentations for scientific and medical meetings. You’ll also prepare briefing documents for regulatory agencies, supporting submissions from INDs through BLAs. With your deep experience in quantitative pharmacology across both clinical and non-clinical settings, you’ll collaborate closely with cross-functional research and clinical teams to drive impactful results. In addition, you will also contribute to business development activities globally.

“At DGr Pharma, you take ownership, have the freedom to drive innovation, and gain broad exposure to drug development, collaborating with international clients in a hands-on, informal culture.” — Kees Groen, CEO DGr Pharma

In this role, you’ll:  

• Coordinate activities within the Clinical Pharmacology and Pharmacokinetics group and communicate with clients.
• Prepare proposals and oversee program progression, including protocols, data analysis, and regulatory interactions.
• You will lead drug development training sessions (with potentially new clients)
• Manage PK/PD, drug interaction, and anti-drug antibody data across all clinical trials.
• Serve as the quantitative clinical pharmacology expert, guiding FIH dose and schedule decisions.
• Contribute to program strategy, study design, execution, data review, reports, and regulatory documents.
• Collaborate with biology and analytical teams on assay development, CRO selection, and management.
• Represent clinical and nonclinical pharmacology in meetings with regulatory authorities.
• Create or guide nonclinical and clinical pharmacology summary documents.
• Stay updated on global regulatory developments and guidance in clinical pharmacology.
• Uphold high standards of good laboratory and clinical practices, compliance, and ethics.

You’ll bring:

The right candidate will drive innovation through collaboration and a constant exchange of ideas.

• MSc or PhD in Life Sciences
• At least 5 years’ work experience in clinical pharmacology/pharmacokinetics with biotech, pharma or regulatory authorities, preferably in a coordinating position. You have experience in the design and execution of clinical I & IIa studies.
• Knowledge of drug development in infectious diseases and oncology is a must-have
• Excellent writing & communication skills: Fluent in English, verbal and Strong interpersonal skills: you will work with clients in Europe and the US
• Strong analytical skills for quantitative data
• Ability to work autonomously on several international projects simultaneously
• Self-starter, result oriented and hands-on
• Proficient with Microsoft Office Word, Excel, and Project
• You are eligible to work in the Netherlands: you own a valid NL working permit

DGr Pharma:

Within DGr Pharma, we focus primarily on Phase I studies, including first-in-human studies, and Phase IIa studies. Assignments include clinical program and study design, related protocol writing, non-compartmental data analysis and report writing.

Location:

Our office is based in Breda, the Netherlands, and working on-site for at least 2 days a week is required. Our team meetings take place on Mondays and Thursdays.

Interested?

Please send your CV and motivational letter to Ningsih Heisterkamp, Corporate Recruiter Symeres: Recruitment@symeres.com. Please make sure to add ‘DGr Pharma’ in the Subject field.

Interview process

The interview process includes a digital pre-screening followed by two live interviews in Breda.