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Lipid-based drug delivery expertise
We provide lipid-based drug delivery expertise, including designing, synthesizing, and manufacturing lipids, with a focus on nucleic acid therapeutics. Our transatlantic teams develop ionizable, helper, and PEGylated lipids, scaling processes to deliver high-purity material for early clinical studies.
This ensures your formulations are optimised for performance, compliant with regulatory standards and ready for clinical success.
Capabilities include:
- Ionizable lipid synthesis and optimization for LNP-based delivery of mRNA, RNAi and other nucleic acid payloads
- Helper and PEGylated lipids to improve particle stability and delivery efficiency
- Small-scale GMP manufacturing (2–250 g) tailored to early clinical trial needs
- Specialized column chromatography purification for high-purity lipid production
- Phase-appropriate support bridging discovery and IND, with flexible, scalable solutions
Related services
Expertise in lipid drug delivery
100+ lipid projects completed
Covering discovery through GMP supply for mRNA vaccines, RNA/DNA therapeutics, and novel delivery platforms.
Gram-scale GMP capacity
Manufacturing and purification of GMP-quality lipid material with full analytical support for early-phase studies.
Purification expertise
Specialized in GMP-ready column chromatography for high-purity lipid production that will meet regulatory needs.
Drug delivery innovation without compromise
Alongside lipid development, we apply polymer and formulation expertise to create delivery systems that perform reliably from discovery to early clinical manufacturing. By
combining capabilities in lipid and polymer chemistry, process development and analytical science, we enable smarter, more versatile delivery strategies – supporting everything from nucleic acid therapeutics to complex small molecules with clarity, quality and speed.
What do our partners say?
“I would like to extend my thanks for the excellent work Symeres has done in synthesizing the API for Part 1 of our project. Your communication throughout the process was outstanding, and the sense of urgency with which you operated allowed us to complete this phase promptly and efficiently.”
Leader
Large biotech
“We are developing the most complex molecule that is built at this time in the world…We work with a lot of CROs, also chemistry CROs, and so far Symeres has done the best job with respect to transparency and also to troubleshoot the problems and find a solution. Over the years we have been really impressed with the work that Symeres has done.”
Founder
Biotech
“A sign that things are going well - we keep coming to you. We’ve given Symeres five or six different projects already. That’s almost unheard of for us.“
Senior Director, Manufacturing
Top 10 global pharma
“The progression was really phenomenal. I am truly impressed. There is a world of difference between you and other CROs.”
Start-up Founder
Biotech
“If the compound can be made, Symeres will undoubtedly find out a good way to make it.”
Dooyoung Jung, CEO
Pinotbio
“Through our dedicated FTE resource at Symeres we have achieved remarkable results, not only by developing a new “aspirational” synthetic route but also by significantly improving the current one to deliver a sustainable route for commercial production and giving us two options for late development.”
Associate Director
Large pharma, Europe
“They’ve always met or exceeded my expectations - that’s why I continue to come back, company after company, year after year.”
Allen Horhota, Vice-President Platform & Delivery
Seamless Therapeutics
“The team is making short work of these targets, so we will have to start thinking of some additional targets!”
Director
Biotech
“We’ve been with them…over 10 years. The cost, the flexibility - the value is just so strong. That’s why we’ve stuck with them.”
Senior Director, CMC
Biotech
Your discovery and development partner
We provide lipid and polymer chemistry expertise across discovery, development, and early clinical manufacturing.
With laboratories in Europe and North America, projects remain closely supported across all phases of drug discovery and development.
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Speak with our lipid drug delivery experts
See how we can support the discovery and development of your next breakthrough.