Quality management systems
Our pharmaceutical quality management systems safeguard your molecule from discovery through GMP manufacturing and regulatory submission. Every process is built on GMP standards and aligned with FDA, EMA, and ICH guidelines to ensure full traceability, data integrity, and reproducibility.
We apply phase-appropriate quality processes that adapt to your program, whether in early discovery, CMC management for pharma, or late-stage IND-enabling support. This unified approach maintains compliance across all Symeres sites and gives you complete confidence in every step of your drug discovery and development journey.
Our global certifications
Symeres operates under GMP, GLP, and ISO-certified systems recognized worldwide. These certifications demonstrate our proven ability to meet global regulatory expectations and deliver reproducible, high-quality results across every project, site and stage of development.
EcoVadis Bronze
Cybervadis Bronze
Science-Based Targets Initiative (SBTi)
Carbon Disclosure Project (CDP)
Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC)
Safety, sustainability and compliance first
We prioritize environmental, health, and safety (EHS) programs across all of our sites.
These programs meet or exceed applicable regulations and cover laboratory safety, waste management, and sustainable practices to minimize environmental impact.
What do our partners say?
“I would like to extend my thanks for the excellent work Symeres has done in synthesizing the API for Part 1 of our project. Your communication throughout the process was outstanding, and the sense of urgency with which you operated allowed us to complete this phase promptly and efficiently.”
Leader
Large biotech
“Through our dedicated FTE resource at Symeres we have achieved remarkable results, not only by developing a new “aspirational” synthetic route but also by significantly improving the current one to deliver a sustainable route for commercial production and giving us two options for late development.”
Associate Director
Large pharma, Europe
“We are developing the most complex molecule that is built at this time in the world…We work with a lot of CROs, also chemistry CROs, and so far Symeres has done the best job with respect to transparency and also to troubleshoot the problems and find a solution. Over the years we have been really impressed with the work that Symeres has done.”
Founder
Biotech
“The team is making short work of these targets, so we will have to start thinking of some additional targets!”
Director
Biotech
“A sign that things are going well - we keep coming to you. We’ve given Symeres five or six different projects already. That’s almost unheard of for us.“
Senior Director, Manufacturing
Top 10 global pharma
“If the compound can be made, Symeres will undoubtedly find out a good way to make it.”
Dooyoung Jung, CEO
Pinotbio
“We’ve been with them…over 10 years. The cost, the flexibility - the value is just so strong. That’s why we’ve stuck with them.”
Senior Director, CMC
Biotech
“The progression was really phenomenal. I am truly impressed. There is a world of difference between you and other CROs.”
Start-up Founder
Biotech
“They’ve always met or exceeded my expectations - that’s why I continue to come back, company after company, year after year.”
Allen Horhota, Vice-President Platform & Delivery
Seamless Therapeutics
Quality success stories
Our quality management and compliance systems have supported biotech and pharma partners through regulatory submissions and audits, ensuring readiness for IND and clinical development.
Our transatlantic locations
Nijmegen, NL (HQ)
Our Nijmegen site serves as the headquarters of our drug discovery
Breda, NL
Home to DGr Pharma: our drug development-focused consultancy
Cranbury, NJ, USA
Home to Exemplify BioPharma: Formulation development, Drug product
Groningen, NL
Oss, NL
Home to Oncolines: precision medicine services in oncology and cancer immunotherapy
Oulu, FL
Home to Admescope. Provides ADME-Tox and pharmacokinetics studies.
Prague, CZ
Weert, NL
Woburn, MA, USA
Home to Organix: integrated chemistry expertise
Resources we think you'll love
CDMO red flags you can’t ignore: Regulatory shortfalls and misalignment
Whitepaper
5 CDMO red flags you can’t ignore: A guide for biotechs and pharma
Whitepaper
CDMO red flags you can’t ignore: Underestimating technology transfer complexity
Blog
O.N.E Symeres: A practical approach to real-world drug development
Whitepaper
CDMO red flags you can’t ignore: Undefined or shifting project scope
Whitepaper
Accelerating chemical innovation: Unveiling Symeres’ parallel chemistry
Webinar | On-demand
From racemic to pure the art and science of enantiomer separation
Whitepaper
IND & IMPD enabling developability roadmap
Whitepaper
Innovations in unnatural amino acids: Advancing functional diversity and applications
Whitepaper
Leveraging copper-catalyzed ullmann-type cross-coupling reactions in PR&D
Whitepaper
Managing nitrosamines in the pharmaceutical industry: A comprehensive approach
Whitepaper
Optimizing solid-state properties and enhancing API bioavailability through physicochemical prediction
Whitepaper
Stable isotope-labeled compounds
Whitepaper
Unlocking the potential of high-throughput screening: Symegold library design and expansion insights
Interviews
Insights into drug discovery and development 2025
Interviews
Interview with the computer-aided drug design (CADD) department
Interviews
Meet the Organix Director, Mario Gonzalez
Interviews
Interview with the new Managing Director of Symeres Groningen
Interviews
An interview with Yadan Chen and Paul O’Shea
Interviews
An interview with Anu Mahadevan and Paul Blundell
Blog
Crystalline and liquid crystalline 25-hydroxy-cholest-5-en-3-sulfate sodium and methods for preparing same
Webinar | On-demand
In vivo pharmacokinetic experiments in preclinical drug development
Webinar | On-demand
Accelerating medicinal chemistry by rapid analoging
Webinar | On-demand
Solid-state chemistry part II: Optimal form selection by controlled crystallization
Webinar | On-demand
Route scouting for kilogram-scale manufacturing of APIs
Webinar | On-demand
Solid-state chemistry part I: Introduction
Speak with our discovery and development experts
See how we can support the discovery and development of your next breakthrough.