Design and synthesis from hit to clinical candidate
Drug discovery is an interdisciplinary science where experience, communication, innovation and speed are key. An experienced interdisciplinary team will work with you on your next clinical candidate.
Symeres delivers high-quality integrated medicinal chemistry services to advance your drug discovery programs: from hit identification to lead optimization and nomination of a clinical candidate. Our teams in Europe and the USA combines highly experienced leadership and project scientists with extensive resources, such as parallel synthesis and purification, supported by our computational chemistry and our Admescope in vitro ADME-Tox and PK platform. Additionally we can integrate a range of in vitro biology capabilities, including Oncolines and ResidenceTimer.
We also have strategic partnerships with carefully selected European CROs for specific biology and structural biology platforms, offering an integrated solution to your Drug Discovery services needs.
This combination of expertise and infrastructure allows the rapid multiparameter expansion and optimization of compound series.
Hit Generation
Discover novel starting points with our advanced screening technologies and expert medicinal chemistry insight.
Hit-to-Lead
Transform initial hits into validated leads through iterative chemistry, screening, and early ADME profiling.
Lead Optimization
Refine promising compounds with data-driven chemistry, ADME-Tox profiling, and biology integration to maximize success.
Computational Chemistry
Accelerate decision-making with predictive modelling, molecular design, and multiparameter optimization.
Rapid Analog Synthesis
Swiftly design, synthesize, and purify compound arrays to accelerate hit exploration and support lead optimization.
Integrated Drug Discovery
Advance from hit to clinical candidate with a seamless, end-to-end partnership combining chemistry, biology, and ADME-Tox expertise.
