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Drug Discovery

From hit finding to clinical candidate identification

Symeres offers best-in-class chemistry solutions for drug discovery and early drug development. Our discovery services span from early stage hit finding to clinical candidate identification.


Our Drug Discovery Services

Hit Generation and Hit to lead activities

Symeres has a strong track record in the validation of hits derived from different screening platforms. Our parallel chemistry capabilities allow us to make many analogs rapidly and cost-effectively.

Lead Optimization

Lead optimization requires multi-parametric fine-tuning. Using our in-house SAR database we efficiently design analogues to progress your lead series toward clinical candidate selection.

Computational Chemistry

From bioisosteric replacements to interactive structure and ligand-based drug design, computational chemistry is an integral part of many of our medicinal chemistry projects. At Symeres we develop modeling approaches tailored to customer requirements.

Rapid Analog Synthesis

High throughput is essential to rapidly explore the chemical space around a hit compound. Symeres has a dedicated team for the design and synthesis of compound arrays, with a focus on novel, 3D scaffolds.

Integrated Drug Discovery

Symeres provides integrated drug discovery for our clients together with our network of centers of excellence.

ADME

In addition to our platform of ADME-Tox services available in our Admescope laboratories, we have a panel of in vitro ADME assays co-located with our medicinal chemistry laboratories in the Netherlands to support multi-parameter optimization.

Admescope

Admescope, a daughter company of Symeres, offers a wide range of ADME services

Hit Generation and Hit to lead activities

Symeres has a strong track record in the validation of hits derived from different screening platforms. Our parallel chemistry capabilities allow us to make many analogs rapidly and cost-effectively.

Lead Optimization

Lead optimization requires multi-parametric fine-tuning. Using our in-house SAR database we efficiently design analogues to progress your lead series toward clinical candidate selection.

Computational Chemistry

From bioisosteric replacements to interactive structure and ligand-based drug design, computational chemistry is an integral part of many of our medicinal chemistry projects. At Symeres we develop modeling approaches tailored to customer requirements.

Rapid Analog Synthesis

High throughput is essential to rapidly explore the chemical space around a hit compound. Symeres has a dedicated team for the design and synthesis of compound arrays, with a focus on novel, 3D scaffolds.

Integrated Drug Discovery

Symeres provides integrated drug discovery for our clients together with our network of centers of excellence.

ADME

In addition to our platform of ADME-Tox services available in our Admescope laboratories, we have a panel of in vitro ADME assays co-located with our medicinal chemistry laboratories in the Netherlands to support multi-parameter optimization

Admescope

Admescope, a daughter company of Symeres, offers a wide range of ADME services

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Development Centres of Excellence Network Lead Optimization Hit Generation Lead Optimization
 
 
 
 
 

Development Centres of Excellence Network Lead Optimization Hit Generation Lead Optimization
 
 
 
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